KANSERLİ HASTALARDA TEK DOZ SUÇİÇEĞİ AŞISININ ETKİNLİĞİ

Cilt: 41 Sayı: 4 1 Aralık 2002
  • Suat Paker
  • Füsun Atlıhan
  • - Pamirgülez
  • Canan Vergin
  • Alpay Özbek
PDF İndir
EN TR

THE EFFICACY OF MONODOSE VARICELLA VACCINE IN PEDIATRIC CANCER PATIENTS

Abstract

In this study the efficacy of a single dose varicella vaccine was evaluated in 20 patients with acute lymphoblastic leukemia and lymphoma. AH patients were serologically negatıve by the absence of antıvaricella antibody. AH cases were in remission for at least 6 months and their absolute lymphocyte count at the time of immunization was ≥ 700/mm3. For patients receiving maintenance therapy, chemotherapy was suspended for 1 week before and 1 week after immunization. Antıvaricella antibody concentration was determined 3 and 24 months after immunization to evaluate antibody response. İn cancer group geometric mean antibody concentration was found 42.78 HU on the 3rd month and 29.3 HU on the 24th month and in the control group the values were 45.98 HU and 31.8. The seropositivity rates were found 90% on the 3rd and on the 24th months in each group. Unserious side effects due to varicella vaccination were determined in 40% of the pediatric cancer group and in 10% of the control group. İn conclusion we can say that single dose varicella vaccine is effective and safe in patients with acute lymphoblastic leukemia and lymphoma.

Keywords

Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

-

Yazarlar

Suat Paker

Füsun Atlıhan

- Pamirgülez

Canan Vergin

Alpay Özbek

Yayımlanma Tarihi

1 Aralık 2002

Gönderilme Tarihi

1 Aralık 2002

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 1970 Cilt: 41 Sayı: 4

Kaynak Göster

Vancouver
1.Suat Paker, Füsun Atlıhan, - Pamirgülez, Canan Vergin, Alpay Özbek. KANSERLİ HASTALARDA TEK DOZ SUÇİÇEĞİ AŞISININ ETKİNLİĞİ. ETD [Internet]. 01 Aralık 2002;41(4):225-8. Erişim adresi: https://izlik.org/JA79PR47NB

Ege Tıp Dergisi, makalelerin Atıf-Gayri Ticari-Aynı Lisansla Paylaş 4.0 Uluslararası (CC BY-NC-SA 4.0) lisansına uygun bir şekilde paylaşılmasına izin verir.