Case Report

Restless Limbs and Bladder: An Atypical Variant of Restless Legs Syndrome Case Report

Volume: 63 Number: 2 June 10, 2024
TR EN

Restless Limbs and Bladder: An Atypical Variant of Restless Legs Syndrome Case Report

Abstract

Restless Legs Syndrome (RLS) primarily affects the legs, but atypical variants involving other body parts have been described. We present a 42-year-old patient presented with 10-year history of urinary urgency along with pain, numbness, and itchiness in the right hand and foot, which worsened and started affecting the left side over the past six months. The symptoms occurred predominantly at night, improved with urination and movement, and affected daily activities. Symptoms completely resolved with pramipexole treatment. The diagnostic criteria for RLS acknowledge atypical variants involving various body parts. Reported cases include genital, bladder, abdominal, bowel, head, oral, and phantom limb variants. Clinicians should consider therapeutic testing, such as with low-dose dopamine agonists, when there is a high clinical suspicion.

Keywords

References

  1. Allen RP, Picchietti DL, Garcia-Borreguero D, et al. Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria – history, rationale, description, and significance. Sleep Med. 2014;15(8):860-873. doi:10.1016/j.sleep.2014.03.025
  2. Turrini A, Raggi A, Calandra-Buonaura G, Martinelli P, Ferri R, Provini F. Not only limbs in atypical restless legs syndrome. Sleep Med Rev. 2018;38:50-55. doi:10.1016/j.smrv.2017.03.007
  3. Prakash S, Prakash A. Dopa responsive headache: Restless head syndrome or a cephalic variant of restless legs syndrome? J Fam Med Prim Care. 2020;9(8):4431. doi:10.4103/jfmpc.jfmpc_640_20
  4. Prakash S, Ahuja S, Rathod C. Dopa responsive burning mouth syndrome: Restless mouth syndrome or oral variant of restless legs syndrome? J Neurol Sci. 2012;320(1-2):156-160. doi:10.1016/j.jns.2012.07.007
  5. Perez-Diaz H, Iranzo A, Rye DB, Santamaria J. Restless abdomen: A phenotypic variant of restless legs syndrome. Neurology. 2011;77(13):1283-1286. doi:10.1212/WNL.0b013e318230207a
  6. Suzuki K, Miyamoto M, Uchiyama T, Miyamoto T, Matsubara T, Hirata K. Restless Bladder in an Elderly Woman: An Unusual Feature or a Variant of Restless Legs Syndrome? Intern Med Tokyo Jpn. 2016;55(18):2713-2716. doi:10.2169/internalmedicine.55.6815
  7. Sforza E, Hupin D, Roche F. Restless Genital Syndrome: Differential Diagnosis and Treatment With Pramipexole. J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med. 2017;13(9):1109-1110. doi:10.5664/jcsm.6736
  8. Nishida S, Hitsumoto A, Namba K, Usui A, Inoue Y. Persistence of secondary restless legs syndrome in a phantom limb caused by end-stage renal disease. Intern Med Tokyo Jpn. 2013;52(7):815-818. doi:10.2169/internalmedicine.52.9013

Details

Primary Language

English

Subjects

Neurology and Neuromuscular Diseases

Journal Section

Case Report

Publication Date

June 10, 2024

Submission Date

October 31, 2023

Acceptance Date

December 19, 2023

Published in Issue

Year 2024 Volume: 63 Number: 2

Vancouver
1.Bekir Burak Kılboz, Raziye Tıraş. Restless Limbs and Bladder: An Atypical Variant of Restless Legs Syndrome Case Report. EJM. 2024 Jun. 1;63(2):319-21. doi:10.19161/etd.1382369

Ege Journal of Medicine enables the sharing of articles according to the Attribution-Non-Commercial-Share Alike 4.0 International (CC BY-NC-SA 4.0) license.