A case of myasthenia gravis emerging after prior diagnosis of CIDP: Clinical challenges in overlapping autoimmune disorders

Şeyma Aykaç; Abdullah Arı; Birgül Dere; Yaprak Seçil; Ayşe Nur Yüceyar

doi:10.19161/etd.1736794

TR EN

A case of myasthenia gravis emerging after prior diagnosis of CIDP: Clinical challenges in overlapping autoimmune disorders

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) and myasthenia gravis (MG) are distinct autoimmune neuromuscular disorders that rarely coexist. We present a 52-year-old man with stable CIDP who developed progressive lower limb weakness and facial involvement. Electrophysiological studies revealed neuromuscular junction dysfunction, and elevated acetylcholine receptor antibodies confirmed MG. Treatment with pyridostigmine, intravenous immunoglobulin, and rituximab resulted in clinical stabilization. This case shows the importance of considering overlapping autoimmune disorders in CIDP patients with new or atypical symptoms. Early recognition using electrophysiological and serological tests is important for accurate diagnosis and effective management of coexisting CIDP and MG.

Keywords

References

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Details

Primary Language

English

Subjects

Neurology and Neuromuscular Diseases

Journal Section

Case Report

Authors

Şeyma Aykaç ^*
0000-0003-3994-0019
Türkiye

Abdullah Arı
0009-0006-1995-210X
Türkiye

Birgül Dere
0000-0002-0565-4922
Türkiye

Yaprak Seçil
0000-0002-8283-9680
Türkiye

Ayşe Nur Yüceyar
0000-0003-4590-6423
Türkiye

Publication Date

December 8, 2025

Submission Date

July 11, 2025

Acceptance Date

September 30, 2025

Published in Issue

Year 2025 Volume: 64 Number: 4

DOI

https://doi.org/10.19161/etd.1736794

IZ

https://izlik.org/JA85WY24HB

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Vancouver

1.Şeyma Aykaç, Abdullah Arı, Birgül Dere, Yaprak Seçil, Ayşe Nur Yüceyar. A case of myasthenia gravis emerging after prior diagnosis of CIDP: Clinical challenges in overlapping autoimmune disorders. EJM. 2025 Dec. 1;64(4):716-20. doi:10.19161/etd.1736794

A case of myasthenia gravis emerging after prior diagnosis of CIDP: Clinical challenges in overlapping autoimmune disorders

Önceden CIDP tanısı almış bir hastada ortaya çıkan miyastenia gravis: Örtüşen otoimmün hastalıklarda klinik zorluklar

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Anahtar Kelimeler

A case of myasthenia gravis emerging after prior diagnosis of CIDP: Clinical challenges in overlapping autoimmune disorders

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite