Multicenter stenotrophomonas maltophilia outbreak associated with arterial blood-gas syringes: Single-center analysis and literature review

Hasip Kahraman; Ceren Büyükdağ; Aynur Dindar; Fatma Erdem

doi:10.19161/etd.1869928

TR EN

Kan gazı şırıngaları ile ilişkili çok merkezli stenotrophomonas maltophilia salgını: Tek merkezli analiz ve literatür derlemesi

Abstract

Amaç: Stenotrophomonas maltophilia, tıbbi cihazlarla ilişkili enfeksiyonlara neden olabilen ve giderek daha sık tanımlanan nozokomiyal bir patojendir. Bu çalışmada, kontamine arterial kan gazı şırıngaları ile ilişkili bir hastane salgını tanımlanmış ve bulgular Türkiye’de aynı dönemde bildirilen eş zamanlı salgınlarla karşılaştırılmıştır. Gereç ve Yöntem: Retrospektif gözlemsel çalışma, … Üniversitesi Hastanesi’nde Eylül 2021–Şubat 2022 döneminde yürütüldü. Aktif sürveyans, çevresel örnekleme ve epidemiyolojik incelemeler gerçekleştirildi. Ayrıca Türkiye’deki eş zamanlı S. maltophilia salgınlarını belirlemek amacıyla odaklanmış bir literatür taraması yapıldı. Bulgular: Toplam 115 hastada klinik S. maltophilia enfeksiyonu saptandı. Kontamine arterial kan gazı şırıngaları salgının kaynağı olarak doğrulandı. Ürünün kullanımının durdurulması ve enfeksiyon kontrol önlemlerinin güçlendirilmesini takiben yeni vaka sayısında hızlı bir düşüş gözlendi. Literatür taraması, aynı dönemde benzer cihaz kaynaklı salgınların da bildirildiğini gösterdi. Sonuç: Ticari olarak üretilen arterial kan gazı şırıngalarının kontaminasyonu, önemli sağlık bakımı ile ilişkili salgınlara yol açabilir. Kaynağın hızlı saptanması, ürün güvenliği izlemi ve ulusal düzeyde koordineli yanıtlar, geniş çaplı yayılımın önlenmesinde kritik öneme sahiptir.

Keywords

Multicenter stenotrophomonas maltophilia outbreak associated with arterial blood-gas syringes: Single-center analysis and literature review

Abstract

Aim: Stenotrophomonas maltophilia is an emerging nosocomial pathogen increasingly recognized as a cause of device-associated infections. We describe a hospital outbreak linked to contaminated arterial blood-gas syringes and compare findings with simultaneous outbreaks reported nationally. Materials and Methods: A retrospective observational study was conducted at … University Hospital between September 2021 and February 2022. Active surveillance, environmental sampling, and epidemiological investigations were performed. A focused literature review was also conducted to identify concurrent S. maltophilia outbreaks in Türkiye. Results: A total of 115 patients with clinical S. maltophilia infections were identified. Contaminated arterial blood-gas syringes were confirmed as the outbreak source. Following the device withdrawal and reinforcement of infection control measures, a rapid decline in new cases was observed. The literature review revealed similar device-associated outbreaks during the same period. Conclusions: Contamination of commercially manufactured arterial blood-gas syringes can lead to significant healthcare-associated outbreaks. Immediate source identification, product surveillance, and coordinated national responses are crucial to prevent widespread transmission.

Keywords

Supporting Institution

This study did not receive any financial support from any institution or organization.

Ethical Statement

This study was approved by the Eskişehir Osmangazi University Non-Interventional Clinical Research Ethics Committee (Approval No: 2024-162; Date: July 16, 2024). The study was conducted retrospectively, and all patient data were anonymized. The requirement for informed consent was waived by the ethics committee.

References

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Details

Primary Language

English

Subjects

Infectious Diseases, Clinical Microbiology

Journal Section

Research Article

Authors

Hasip Kahraman ^*
0000-0002-5120-4877
Türkiye

Ceren Büyükdağ
0000-0003-1067-2516
Türkiye

Aynur Dindar
0009-0000-3062-5018
Türkiye

Fatma Erdem
0000-0002-5310-313X
Türkiye

Publication Date

June 10, 2026

Submission Date

January 23, 2026

Acceptance Date

February 5, 2026

Published in Issue

Year 2026 Volume: 65 Number: 2

DOI

https://doi.org/10.19161/etd.1869928

IZ

https://izlik.org/JA68HK28PB

Cite

RIS / Bibtex

APA

Kahraman, H., Büyükdağ, C., Dindar, A., & Erdem, F. (2026). Multicenter stenotrophomonas maltophilia outbreak associated with arterial blood-gas syringes: Single-center analysis and literature review. Ege Tıp Dergisi, 65(2), 275-282. https://doi.org/10.19161/etd.1869928

AMA

1.Kahraman H, Büyükdağ C, Dindar A, Erdem F. Multicenter stenotrophomonas maltophilia outbreak associated with arterial blood-gas syringes: Single-center analysis and literature review. EJM. 2026;65(2):275-282. doi:10.19161/etd.1869928

Chicago

Kahraman, Hasip, Ceren Büyükdağ, Aynur Dindar, and Fatma Erdem. 2026. “Multicenter Stenotrophomonas Maltophilia Outbreak Associated With Arterial Blood-Gas Syringes: Single-Center Analysis and Literature Review”. Ege Tıp Dergisi 65 (2): 275-82. https://doi.org/10.19161/etd.1869928.

EndNote

Kahraman H, Büyükdağ C, Dindar A, Erdem F (June 1, 2026) Multicenter stenotrophomonas maltophilia outbreak associated with arterial blood-gas syringes: Single-center analysis and literature review. Ege Tıp Dergisi 65 2 275–282.

IEEE

[1]H. Kahraman, C. Büyükdağ, A. Dindar, and F. Erdem, “Multicenter stenotrophomonas maltophilia outbreak associated with arterial blood-gas syringes: Single-center analysis and literature review”, EJM, vol. 65, no. 2, pp. 275–282, June 2026, doi: 10.19161/etd.1869928.

ISNAD

Kahraman, Hasip - Büyükdağ, Ceren - Dindar, Aynur - Erdem, Fatma. “Multicenter Stenotrophomonas Maltophilia Outbreak Associated With Arterial Blood-Gas Syringes: Single-Center Analysis and Literature Review”. Ege Tıp Dergisi 65/2 (June 1, 2026): 275-282. https://doi.org/10.19161/etd.1869928.

JAMA

1.Kahraman H, Büyükdağ C, Dindar A, Erdem F. Multicenter stenotrophomonas maltophilia outbreak associated with arterial blood-gas syringes: Single-center analysis and literature review. EJM. 2026;65:275–282.

MLA

Kahraman, Hasip, et al. “Multicenter Stenotrophomonas Maltophilia Outbreak Associated With Arterial Blood-Gas Syringes: Single-Center Analysis and Literature Review”. Ege Tıp Dergisi, vol. 65, no. 2, June 2026, pp. 275-82, doi:10.19161/etd.1869928.

Vancouver

1.Hasip Kahraman, Ceren Büyükdağ, Aynur Dindar, Fatma Erdem. Multicenter stenotrophomonas maltophilia outbreak associated with arterial blood-gas syringes: Single-center analysis and literature review. EJM. 2026 Jun. 1;65(2):275-82. doi:10.19161/etd.1869928