AN EXPERIMENTAL SET-UP TO ANALYSE EXPIRATORY GASES AND TO MEASURE VENTILATION IN SPONTANEOUSLY BREATHING GUINEA PIGS UNDER ANAESTHESIA

Volume: 39 Number: 3 September 1, 2000
  • Mustafa Özbek
  • Tamer Zeren
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AN EXPERIMENTAL SET-UP TO ANALYSE EXPIRATORY GASES AND TO MEASURE VENTILATION IN SPONTANEOUSLY BREATHING GUINEA PIGS UNDER ANAESTHESIA

Abstract

The analysers which determinate oxygen fraction in a mixed gases paramagnetically, vvorks by suction of the mixed gas with a certain flow rate. The gas analyser used in this study needs a flow of gas of 210 mimin1. This rate was near of ventilation value of spontaneously breathing small laboratory animal. Therefore, a direct connection of such an analyser to output of respiratory system causes a great error of measurement. To solve this problem, the expired gas was collected in a room with the aid of respiratory micro valve and in order to determinate fractions of both oxygen and carbondioxide, the input of analyser was connected to this room. The ventilation measurement was performed by a pneumotachograph incorporated into the experimental set-up used. The oxygen uptake and carbon dioxide release vvere found 8.03 ± 0.68 ml.min'1 STPD and 7.38 ± 0.70 mimin1 STPD respectively in guinea pigs with body weights between 0.85 and 1.0 kg under neuroleptanaesthesia. These values reflect spontaneous respiratory function of anaesthetized guinea pigs with normal blood-gas values.

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Primary Language

Turkish

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Journal Section

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Authors

Mustafa Özbek

Tamer Zeren

Publication Date

September 1, 2000

Submission Date

September 1, 2000

Acceptance Date

-

Published in Issue

Year 2000 Volume: 39 Number: 3

IZ

https://izlik.org/JA87PD28FD

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1.Mustafa Özbek, Tamer Zeren. ANESTEZİ ALTINDA SPONTAN SOLUNUM YAPAN KOBAYLARDA EKSPİRASYON GAZLARININ ANALİZİ VE VENTİLASYON ÖLÇÜMÜ İÇİN BİR DENEYSEL DÜZENEK. EJM [Internet]. 2000 Sep. 1;39(3):169-72. Available from: https://izlik.org/JA87PD28FD

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