NONSPECIFIC BRONCHIAL HYPERREACTIVITY İN PATIENTS WITH ALLERGIC RHINITIS AND ITS RELATIONSHIP WITH SERUM EOSINOPHILIC CATİONİC PROTEİN

Volume: 39 Number: 3 September 1, 2000
  • Ali Kokuludağ
  • Nihal Erdem
  • Münevver Erdinç
  • Ender Terzioğlu
  • Filiz Sebik
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NONSPECIFIC BRONCHIAL HYPERREACTIVITY İN PATIENTS WITH ALLERGIC RHINITIS AND ITS RELATIONSHIP WITH SERUM EOSINOPHILIC CATİONİC PROTEİN

Abstract

A link betvveen allergic rhinitis and asthma has been knovvn for a long time. Allergic rhinitis may precede to asthma. Nonasthmatic patients with allergic rhinitis may have bronchial hyperreactivity. The aim of this study was to investigate both the prevalance of bronchial hyperreactivity in patients vvith allergic rhinitis vvithout any asthmatic symptoms and a possible relationship betvveen bronchial hyperreactivity and serum eosinophil cationic protein. Fourthynine patients with allergic rhinitis were included in this study. Bronchial challenges vvere performed vvith increasing concentrations of metacholine. The serum concentrations of eosinophil cationic protein vvere measured vvith a commercially available fluoroimmunoassay kit. Bronchial hyperreactivity was found in 18 (36.7%) patients. The mean age of the patients vvith perennial allergic rhinitis who have bronchial hyperreactivity was less than the mean age of the patients vvith seasonal allergic rhinitis. The prevalance of bronchial hyperreactivity increased as the disease progressed, in the perennial allergic rhinitis group. Serum eosinophil cationic protein levels of patients vvith bronchial hyperreactivity vvere higher than those of patients vvithout bronchial hyperreactivity. No correlation vvas found betvveen serum eosinophil cationic protein levels and bronchial hyperreactivity. In conclusion, it seems Tike an important percent of allergic rhinitis patients have a bronchial reactivity vvithout asthmatic symptoms.

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Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Ali Kokuludağ

Nihal Erdem

Münevver Erdinç

Ender Terzioğlu

Filiz Sebik

Publication Date

September 1, 2000

Submission Date

September 1, 2000

Acceptance Date

-

Published in Issue

Year 2000 Volume: 39 Number: 3

IZ

https://izlik.org/JA73UW27RN

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RIS / Bibtex
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1.Ali Kokuludağ, Nihal Erdem, Münevver Erdinç, Ender Terzioğlu, Filiz Sebik. ALLERJİK RİNİTLİ HASTALARDA NONSPESİFİK BRONŞ HİPERREAKTİVİTESİ VE SERUM EOSİNOFİLİK KATYONİK PROTEİN İLE İLİŞKİSİ. EJM [Internet]. 2000 Sep. 1;39(3):193-8. Available from: https://izlik.org/JA73UW27RN

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