THE EFFECTS OF LIDOCAINE AND DILTIAZEM ON HAEMODYNAMIC CHANGES DURING TRACHEAL EXTUBATION

Volume: 41 Number: 4 December 1, 2002
  • Abdürrahim Derbent
  • Kubilay Demirağ
  • Taner Balcıoğlu
  • Elvin Kurdoğlu
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THE EFFECTS OF LIDOCAINE AND DILTIAZEM ON HAEMODYNAMIC CHANGES DURING TRACHEAL EXTUBATION

Abstract

Increased sympathetic response to surgical stimulation in craniotomy cases, comes out at the end of the operation with discontinuation of anesthetics. Depressing the haemodynamic response on these cases is important for the postoperative prognosis of the patients. In this study, the haemodynamic effects of diltiazem and lidocaine given intravenously just before extubation in patients undergoing craniotomy, is investigated. With approval by the Local Ethics Committee of the University Hospital of Ege and after obtaining informed consent, 30 patients ASA I - II, between the ages 18-60 were randomly assigned to two groups. After standardised induction of anesthesla, 50-50% N2O - O2 and sevoflurane 2-2.5 % were used for the malntenance of anesthesia. Intraoperative haemodynamic changes were recorded. In Group D patients received dlltiazem 0.2 mg/kg, in Group L patients received lidocaine 0.1 mg/ kg intravenously 2 minutes before extubation. Heart rate (HR), systolic arterial pressure (SAP), mean arterial pressure (MAP) were recorded just before extubation, after extubation, 1., 2., 5. and 10. min after extubation. RPP (rate pressure product) were calculated from (RPP = HR x SAP) formulas. Assesment for the quality of tracheal extubation was made with 5 points scale when extubation performed. Despite no significant difference in diltiazem group observed in anytime, SAP increased in lidocaine group at the 1st, 2nd, 5m and 10m minutes after extubation (p

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Primary Language

Turkish

Subjects

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Journal Section

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Authors

Abdürrahim Derbent

Kubilay Demirağ

Taner Balcıoğlu

Elvin Kurdoğlu

Publication Date

December 1, 2002

Submission Date

December 1, 2002

Acceptance Date

-

Published in Issue

Year 2002 Volume: 41 Number: 4

IZ

https://izlik.org/JA96LG33RU

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1.Abdürrahim Derbent, Kubilay Demirağ, Taner Balcıoğlu, Elvin Kurdoğlu. KRANİYOTOMİ OLGULARINDA OİLTİAZEM VE LİDOKAİN’İN EKSTÜBASYONDA HEMODİNAMİK DEĞİŞİKLİKLERE ETKİSİ. EJM [Internet]. 2002 Dec. 1;41(4):233-6. Available from: https://izlik.org/JA96LG33RU

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