ALTERATIONS IN SERUM THYROID HORMONES, LIPIDS AND DEHYDROEPIANDROSTERONE SULFATE LEVELS IN THE FASTING AND POSTPRANDIAL STATES

Volume: 43 Number: 1 March 1, 2004
  • Kadir Gülsün
  • Fatma Taneli
  • Füsun ERCİ Yas
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ALTERATIONS IN SERUM THYROID HORMONES, LIPIDS AND DEHYDROEPIANDROSTERONE SULFATE LEVELS IN THE FASTING AND POSTPRANDIAL STATES

Abstract

Biochemical tests are known to be affected by fasting or postprandial state. The aim of the present study is to assess the possible alterations between the fasting and postprandial serum levels of total triiodothyronine (T3), total thyroxine (T4), free T3, free T4, thyroid stimulating hormone (TSH) dehydroepiandrosterone sulfate (DHEA-SO4) and lipids. In 35 healthy cases blood samples were obtained aftera 12-hour-fasting period at 08:00-09:00 hours and postprandial samples after 2 hours at 10:00-11:00 hours. In both groups of samples, serum lipids (total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, VLDL cholesterol), thyroid hormones and DHEA-SO4 were assayed on the same day. Total cholesterol, triglyceride and HDL cholesterol were analyzed on an automatic analyzer by enzymatic methods, thyroid hormones by cheiluminescence and DHEA-SO4 by radioimmunoassay. Fasting triglyceride, VLDL and DHEA-SO4 values were significantly (p=0.042, p=0.038 and p=0.002, respectively) lower than the postprandial values, while fasting LDL cholesterol and TSH values were found significantly (p=0.027, p=0.002, respectively) higher than the postprandial values. However, no differences were found between the postprandial and fasting values of total T3, total T4, free T3 and free T4. In conclusion, to avoid preanalitical errors especially serum TSH and DHEA-SO4 levels should be assessed on samples obtained after a 12-hour-fasting period.

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Primary Language

Turkish

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Journal Section

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Authors

Kadir Gülsün

Fatma Taneli

Füsun ERCİ Yas

Publication Date

March 1, 2004

Submission Date

March 1, 2004

Acceptance Date

-

Published in Issue

Year 2004 Volume: 43 Number: 1

IZ

https://izlik.org/JA52ZP72ZL

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1.Kadir Gülsün, Fatma Taneli, Füsun ERCİ Yas. SERUM TİROİD HORMONLARI, LİPİD PARAMETRELERİ VE DEHİDROEPİANDROSTERON SÜLFAT DÜZEYLERİNİN AÇLIK VE TOKLUKLA İLİŞKİSİ. EJM [Internet]. 2004 Mar. 1;43(1):15-8. Available from: https://izlik.org/JA52ZP72ZL

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