POSTOPERATIVE RADIOTHERAPY IN ENDOMETRIAL CARCINOMA : ANALYSIS OF TREATMENT RESULTS AND PROGNOSTIC FACTORS IN 509 PATIENTS

Volume: 43 Number: 3 September 1, 2004
  • Arif Aras
  • Özlem Demir
  • Ayfer Haydaroğlu
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POSTOPERATIVE RADIOTHERAPY IN ENDOMETRIAL CARCINOMA : ANALYSIS OF TREATMENT RESULTS AND PROGNOSTIC FACTORS IN 509 PATIENTS

Abstract

Five-hundred-nine patients with endometrial carcinoma who received postoperative radiotherapy between January 1992-December 2001 were evaluated retrospectively to determine the overall disease-free and local-recurrence free survival rates and prognostic factors affecting survival. Median age was 58 (range: 31-83). Histologically 88.0% were adenocarcinoma, 6.1% adenosquamous carcinoma, 4.3% clear-cell carcinoma and 1.6% serous papillary carcinoma. The distribution by stages were: 65.1% Stage I, 17.7% Stage II, 14.6% Stage III, 2.8% Stage IVA. All patients received median 54 Gy external radiotherapy with 1.8-2.0 Gy daily fractions. Intracavitary brachytherapy was applied to 463 cases. Median follow-up time was 68 months (range: 6-141 months). Survival analysis was performed using the Kaplan-Meier method. Log-rank test was used for univariate analysis and Cox regression test was used for multivariate analysis. Five-year overall, disease-free and local recurrence-free survival rates were 80.5%, 85.1% and 91.2% respectively. According to univariate analysis prognostic factors influencing local control were histology (p=0.001),stage (p

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Primary Language

Turkish

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Journal Section

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Authors

Arif Aras

Özlem Demir

Ayfer Haydaroğlu

Publication Date

September 1, 2004

Submission Date

September 1, 2004

Acceptance Date

-

Published in Issue

Year 2004 Volume: 43 Number: 3

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https://izlik.org/JA23NA75WT

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1.Arif Aras, Özlem Demir, Ayfer Haydaroğlu. POSTOPERATİF RADYOTERAPİ UYGULANAN ENDOMETRİUM KANSERLİ OLGULARDA TEDAVİ SONUÇLARI VE PROGNOSTİK FAKTÖRLER : 509 OLGUNUN DEĞERLENDİRİLMESİ. EJM [Internet]. 2004 Sep. 1;43(3):169-74. Available from: https://izlik.org/JA23NA75WT

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