THE EFFECT OF HORMONE REPLACEMENT TREATMENT TO MAMMOGRAPHIC PARENCHYMA DENSITY

Volume: 45 Number: 2 June 1, 2006
  • A.Ender Yumru
  • Murat Bozkurt
  • Nuh Gümüştekin
  • Y.Tahsin Ayanoğlu
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THE EFFECT OF HORMONE REPLACEMENT TREATMENT TO MAMMOGRAPHIC PARENCHYMA DENSITY

Abstract

Aim: In this study the aims are to determine the relation between parenchymal density varieties and hormone replacement treatment (HRT) among the patients who receive HRT, to count the increase of density with this treatment regime, and to compare the mammographic density varieties among postmenopausal patient groups that use different hormone preparats. Material and Methods: A study design was used with 82 patients who applied to menopause policlinic of Taksim Education and Research Hospital and who were diagnosed as having menopause there between 05.01.1999 and 01.03.2003. One of the groups was constituted by 32 patients who were operated with TAH+BSO. This group received continuous estrogen treatment. The others were divided into groups according to different hormone replacement regimes. Every year the parenchymal density varieties of the patients was analyzed with mammography by dividing into 10 groups. Signs: These results are determined according to Wolfe classification among all the patients who receive HRT: • Mammographic density increase %24.3 (n:20) • Mammographic density decrease %7.3 (n:6) • Stabil mammographic density %68.2 (n:56) (note: ‘n' means number) The results of the patients who received continuous estrogen treatment (Climara tts, premarin and estrofem oral tab) are: %25 increase (n:8), %3.1decrease (n:1), %71.8 stabil (n:83). The results of the group who received continuous estrogen and progesterone combined HRT are: %41.6 increase (n:10), %0 decrease (n:0), %58.3 stabil (n:14). The results of the group who received tibolon (Livial oral tab.) are: %7.6 increase (n:2), %19.2 decrease (n:5), %73 stabil (n:19). Results: In our study, the group which reported the most increasing mammographic parenchymal density was the group which received combined estrogen and progesterone. In this group density increasing was %41.6 ratio. The lowest increasing density level was reported with the group which received Tibolon and ratio was %7.6.

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Primary Language

Turkish

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Journal Section

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Authors

A.Ender Yumru

Murat Bozkurt

Nuh Gümüştekin

Y.Tahsin Ayanoğlu

Publication Date

June 1, 2006

Submission Date

June 1, 2006

Acceptance Date

-

Published in Issue

Year 2006 Volume: 45 Number: 2

IZ

https://izlik.org/JA52ZX84PR

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1.A.Ender Yumru, Murat Bozkurt, Nuh Gümüştekin, Y.Tahsin Ayanoğlu. HORMON REPLASMAN TEDAVİSİNİN MAMOGRAFİK PARANKİM DANSİTESİ ÜZERİNE ETKİSİ. EJM [Internet]. 2006 Jun. 1;45(2):109-14. Available from: https://izlik.org/JA52ZX84PR

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