HUNTINGTON HASTALIĞI: İKİ OLGU

Nurşen Kömürcülü; Aysun İnce; Ebru Bakar; Hikmet Yılmaz; İnanç Karapolat; Deniz Selçuki

EN TR

CASE REPORT: TWO PATIENTS WITH HUNTINGTON'S DISEASE

Abstract

Huntington's disease is an autosomal dominantly transmitted, progressive neuro-degenerative disease which presents itself with motor, psychiactric and cognitive dysfunction. Diagnosis of genetically transmitted disease is important in many aspects. 56 year-old female and 61year-old male patients referred to the hospital with compliants of forgetfulness, involuntary movements and depressive-like symtoms. The female patients cranial magnetic resonans imagining (MRI) showed diffuse atrophy and the male patient's MRI was notable for fokal areas of atrophies mainly in the caudate and putamen nuclei. In PET( Positron emission tomography) examination low methabolic activity of FDG in the caudate nucleus of both patients supported the diagnosis the genetic results of N19/Exp43 CAG. The clinical significance of PET study was stated in two genetically diafnascd cases with, Huntington's diseas.

Keywords

Huntington's disease , PET

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Nurşen Kömürcülü

Aysun İnce

Ebru Bakar

Hikmet Yılmaz

İnanç Karapolat

Deniz Selçuki

Publication Date

June 1, 2006

Submission Date

June 1, 2006

Acceptance Date

-

Published in Issue

Year 1970 Volume: 45 Number: 2

IZ

https://izlik.org/JA58BM75HP

Cite

RIS / Bibtex

Vancouver

1.Nurşen Kömürcülü, Aysun İnce, Ebru Bakar, Hikmet Yılmaz, İnanç Karapolat, Deniz Selçuki. HUNTINGTON HASTALIĞI: İKİ OLGU. EJM [Internet]. 2006 Jun. 1;45(2):139-43. Available from: https://izlik.org/JA58BM75HP

CASE REPORT: TWO PATIENTS WITH HUNTINGTON'S DISEASE

CASE REPORT: TWO PATIENTS WITH HUNTINGTON'S DISEASE

Abstract

Keywords