EFFECT OF HEPARIN ON HUMAN SKIN FIBROBLAST PROLIFERATION IN VITRO

Volume: 45 Number: 3 September 1, 2006
  • Berna Yılmaz
  • Çığır Biray Avcı
  • Cumhur Gündüz
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EFFECT OF HEPARIN ON HUMAN SKIN FIBROBLAST PROLIFERATION IN VITRO

Abstract

The dose-related effects of standard heparin on the proliferation of cultured human skin fibroblasts were investigated in the cell cultures which were established using human skin biopsy material. It was determined that the high concentrations [1/2 -1/64, (2500-78 IU/ml)] of standard heparin was cytotoxic. In low concentrations [1/128-1/1024, (39-5 IU/ml)], heparin showed an effect in proliferation way. The correlation between heparin concentration and the proliferation of cultured human skin fibroblasts was found to be 90 % and this result is statistically significant (p

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Primary Language

Turkish

Subjects

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Journal Section

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Authors

Berna Yılmaz

Çığır Biray Avcı

Cumhur Gündüz

Publication Date

September 1, 2006

Submission Date

September 1, 2006

Acceptance Date

-

Published in Issue

Year 2006 Volume: 45 Number: 3

IZ

https://izlik.org/JA35SE98RR

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1.Berna Yılmaz, Çığır Biray Avcı, Cumhur Gündüz. IN VITRODA HEPARİNİN İNSAN DERİ FİBROBLASTLARININ ÇOĞALMASI ÜZERİNDEKİ ETKİSİ. EJM [Internet]. 2006 Sep. 1;45(3):175-8. Available from: https://izlik.org/JA35SE98RR

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