Beta -2 mikroglobulin amiloidozu (Aβ2M) (diyalizle ilişkili amiloidoz)

Sarsık B; Doğanavşargil B; Bozkurt D; Şen S

EN TR

Beta-2 microglobulin amyloidosis (Aβ2M) (dialysis related amyloidosis)

Abstract

Dialysis-related amyloidosis secondary to β2 microglobulin deposition is a complication of long-term dialysis. Beta2 microglobulin has a tendency to deposit in the osteoarticular tissues, particularly in large bones and in synovial membranes. Clinical manifestations include carpal tunnel syndrome, destructive arthropathy, bone cysts and fractures. We diagnosed a patient with β2 microglobulin amyloidosis in whom cystic lesion and destructive arthropathy were clinically showed. The patient was a 53-year-old man who had been on hemodialysis for more than 15 years because of end-stage renal disease. Congo red staining and β2 microglobulin immunohistochemistry, showed extended β2 microglobulin deposits in the operation material was taken because of the pathological fracture of femur .

Keywords

Beta-2-microglobulin, dialysis, amiloidosis, end stage renal disease

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Sarsık B

Doğanavşargil B

Bozkurt D

Şen S

Publication Date

June 1, 2009

Submission Date

June 1, 2009

Acceptance Date

-

Published in Issue

Year 1970 Volume: 48 Number: 2

IZ

https://izlik.org/JA88WW45LZ

Cite

RIS / Bibtex

Vancouver

1.Sarsık B, Doğanavşargil B, Bozkurt D, Şen S. Beta -2 mikroglobulin amiloidozu (Aβ2M) (diyalizle ilişkili amiloidoz). EJM [Internet]. 2009 Jun. 1;48(2):139-43. Available from: https://izlik.org/JA88WW45LZ

Beta-2 microglobulin amyloidosis (Aβ2M) (dialysis related amyloidosis)

Beta-2 microglobulin amyloidosis (Aβ2M) (dialysis related amyloidosis)

Abstract

Keywords