Pediatrik lupus nefritinin retrospektif izlem sonuçları, tek merkez çalışması

Sozeri B; Mir S; Mutlubas F; En S

EN TR

Retrospective analysis of the outcome of pediatric lupus nephritis, single center study

Abstract

Aim: We aim to analyse in this study was outcome results and therapy modalities in patients with lupus nephritis. Materials and Methods: We performed a retrospective cohort study of our 37 lupus patients, diagnosed and treated between1986-2006. Conclusions: The mean age at onset of disease was 13 ± 2.2 years. Renal involvement was present in 26 (70.2%) of the patients. At the time of the initial biopsy, proteinuria was observed in 15 (57.7%) patients, and it was within nephrotic range in 4 (15.3%) patients. 11 (42.3%) patients had hematuria, 7 (26.9%) had hypertension, and 6 (23%) had impaired renal function. The most frequent histopathological finding was class II (42.3%), followed by class IV (30.7%), class III (15.3%) and class I (11.7%) lupus nephritis (LN). All patients with class IV lupus nephritis had a significant tendency for developing hypertension (p=0.006) and nephrotic range proteinuria (p=0.004). 57% of patients with lupus nephritis had remission, 30% of them still had active disease. Result: Finally, the prognosis of children with LN depends primarily on the severity of histopathological lesions.

Keywords

Systemic lupus erthematosus, lupus nephritis, childhood, therapy, outcome

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Sozeri B

Mir S

Mutlubas F

En S

Publication Date

September 1, 2009

Submission Date

September 1, 2009

Acceptance Date

-

Published in Issue

Year 2009 Volume: 48 Number: 3

IZ

https://izlik.org/JA72NF95UK

Cite

RIS / Bibtex

APA

B, S., S, M., F, M., & S, E. (2009). Pediatrik lupus nefritinin retrospektif izlem sonuçları, tek merkez çalışması. Ege Tıp Dergisi, 48(3), 181-187. https://izlik.org/JA72NF95UK

AMA

1.B S, S M, F M, S E. Pediatrik lupus nefritinin retrospektif izlem sonuçları, tek merkez çalışması. EJM. 2009;48(3):181-187. https://izlik.org/JA72NF95UK

Chicago

B, Sozeri, Mir S, Mutlubas F, and En S. 2009. “Pediatrik Lupus Nefritinin Retrospektif Izlem Sonuçları, Tek Merkez çalışması”. Ege Tıp Dergisi 48 (3): 181-87. https://izlik.org/JA72NF95UK.

EndNote

B S, S M, F M, S E (September 1, 2009) Pediatrik lupus nefritinin retrospektif izlem sonuçları, tek merkez çalışması. Ege Tıp Dergisi 48 3 181–187.

IEEE

[1]S. B, M. S, M. F, and E. S, “Pediatrik lupus nefritinin retrospektif izlem sonuçları, tek merkez çalışması”, EJM, vol. 48, no. 3, pp. 181–187, Sept. 2009, [Online]. Available: https://izlik.org/JA72NF95UK

ISNAD

B, Sozeri - S, Mir - F, Mutlubas - S, En. “Pediatrik Lupus Nefritinin Retrospektif Izlem Sonuçları, Tek Merkez çalışması”. Ege Tıp Dergisi 48/3 (September 1, 2009): 181-187. https://izlik.org/JA72NF95UK.

JAMA

1.B S, S M, F M, S E. Pediatrik lupus nefritinin retrospektif izlem sonuçları, tek merkez çalışması. EJM. 2009;48:181–187.

MLA

B, Sozeri, et al. “Pediatrik Lupus Nefritinin Retrospektif Izlem Sonuçları, Tek Merkez çalışması”. Ege Tıp Dergisi, vol. 48, no. 3, Sept. 2009, pp. 181-7, https://izlik.org/JA72NF95UK.

Vancouver

1.Sozeri B, Mir S, Mutlubas F, En S. Pediatrik lupus nefritinin retrospektif izlem sonuçları, tek merkez çalışması. EJM [Internet]. 2009 Sep. 1;48(3):181-7. Available from: https://izlik.org/JA72NF95UK