Treatment results of glycolic acid and glycolic acid / topical lightening therapy in melasma: A retropective analysis

Volume: 52 Number: 2 June 1, 2013
  • Ertam İ
  • Sezgin A Ö
  • Ünal İ
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Treatment results of glycolic acid and glycolic acid / topical lightening therapy in melasma: A retropective analysis

Abstract

Introduction: The objective of this study is to examine the demographic properties of the melasma patients and the treatment response to only glycolic acid (GA) or GA + topical melasma skin lightening treatment. Materials and Methods: Between 2005 and 2009, 200 patients attending our clinic due to melasma were retrospectively analyzed. The patients were divided into three groups: Only chemical peeling with GA (Group I), GA chemical peeling with topical treatment (Group II) and only topical treatment (Group III). Pretreatment and posttreatment MASI (Melasma Area and Severity Index) scores were calculated with the assessment of the patient's photographs. Results: The mean age of the patients was 37.71±6.97 years. Pretreatment MASI scores were between 1.4-20.6 (7.64±3.82), MASI last scores were between 0.6-20 (4.62±3.30). There were 41 patients (20.5%) in Group I, 100 patients (50%) in Group II, 47 patients (23.5%) in Group III. When the difference between MASI first and last scores were evaluated separately (Group I and Group II), a statistically significant difference was found in both in two groups (p0.05). Conclusion: In this study, both in the usage of GA alone and combination with topical treatments, MASI was found to decrease significantly. However, there was no statistical difference in the proportion of the decrease of MASI between these two treatment modality.

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Primary Language

Turkish

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Journal Section

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Authors

Ertam İ

Sezgin A Ö

Ünal İ

Publication Date

June 1, 2013

Submission Date

June 1, 2013

Acceptance Date

-

Published in Issue

Year 2013 Volume: 52 Number: 2

IZ

https://izlik.org/JA23GW73DH

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1.Ertam İ, Sezgin A Ö, Ünal İ. Melazmada glikolik asit ve glikolik asit / topikal leke açıcı tedavi sonuçları: Retrospektif bir değerlendirme. EJM [Internet]. 2013 Jun. 1;52(2):100-3. Available from: https://izlik.org/JA23GW73DH

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