Intrastromal voriconazole application in the topical treatment of resistant Aspergillus fumigatus keratitis

Volume: 53 Number: 1 March 1, 2014
  • Yuksel B
  • Calik S
  • Pehlivan O
  • Topcu B
  • Calik B
Ege Journal of Medicine Cover
Ege Journal of Medicine
PDF Download
EN TR

Intrastromal voriconazole application in the topical treatment of resistant Aspergillus fumigatus keratitis

Abstract

To evaluate the results of the application of intrastromal voriconazole in the topical treatment of resistant Aspergillus fumigatus. We present an interventional case report. A 50 mg/0.1 mL solution of voriconazole was injected into the corneal stromal tissue around the infiltration and put on topical voriconazole (1%) after the ulcer had failed to respond to 0.15% (1.5 mg/ml) topical amphotericin B hourly and systemic convantional amphotericin B (0.1 mg/kg) per day. Clinical outcomes were assessed at each visit. After the intervention, a faster reduction in the corneal infiltration and a dramatic therapeutic reponse was observed in the patient.

Keywords

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Yuksel B

Calik S

Pehlivan O

Topcu B

Calik B

Publication Date

March 1, 2014

Submission Date

March 1, 2014

Acceptance Date

-

Published in Issue

Year 2014 Volume: 53 Number: 1

DOI

https://doi.org/10.19161/etd.344041

IZ

https://izlik.org/JA63NA73LP

Cite

RIS / Bibtex
Vancouver
1.Yuksel B, Calik S, Pehlivan O, Topcu B, Calik B. Topikal tedaviye dirençli Aspergillus fumigatus keratitinde intrastromal vorikonazol uygulaması. EJM. 2014 Mar. 1;53(1):49-52. doi:10.19161/etd.344041

Ege Journal of Medicine enables the sharing of articles according to the Attribution-Non-Commercial-Share Alike 4.0 International (CC BY-NC-SA 4.0) license.