Incidence and clinical importance of prostate cancer in patients who underwent radical cystoprostatectomy

Volume: 54 Number: 2 June 1, 2015
  • Hakan Türk
  • Mustafa Karabıçak
  • Sıtkı Ün
  • Hüseyin Tarhan
  • Okan Nabi Yalbuzdağ
  • Naciye Ümit Bayol
  • Tufan Süelözgen
  • Cemal Selçuk İşoğlu
  • Ferruh Zorlu
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Incidence and clinical importance of prostate cancer in patients who underwent radical cystoprostatectomy

Abstract

Aim: Incidental prostate adenocarcinomas which are detected in radical cystoprostatectomy (RCP) specimens are generally localized, well differentiated and have no clinical importance. In this study, we aimed to determine the rate of incidental prostate adenocarcinoma in patients underwent RCP and assess its effect on survival of the patients. Materials and Methods: The patients who underwent RCP for urothelial bladder cancer between September 2007 and March 2014 were analyzed retrospectively. Deep muscle invasion of urothelial carcinoma or high grade transitional epithelial cell carcinoma that could not be controlled by transurethral resection were the indications for surgery. Standard RCP and bilaterally expanded pelvic lymphadenectomy were performed in all patients. All samples of the cystoprostatectomy specimen were examined; Gleason degree of tumor, concurrent prostatic intraepithelial neoplasia, extracapsular extension, invasion of seminal vesicle, and metastasis of lymph nodes were evaluated. Results: Incidental prostate adenocarcinoma was diagnosed in 26 of 126 patients (20.6%) who underwent RCP for bladder urothelial carcinoma. The stages of prostate cancer were pT2a in 16 patients (61.5%), pT2c in 8 patients (30.7%), and T3b in 2 patients (7.6%). Gleason score was detected as lower than 6 in 18 patients, 7 (4+3) in 6 patients, and 9 (5+4) in 2 patients. Conclusion: All prostate tissue should be resected with no residual prostate tissue left in patients who underwent RCP for bladder cancer. The high coincidence of bladder and prostate cancers should be kept in mind, careful and detailed pathological examinations are needed.

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Primary Language

Turkish

Subjects

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Journal Section

-

Authors

Hakan Türk

Mustafa Karabıçak

Sıtkı Ün

Hüseyin Tarhan

Okan Nabi Yalbuzdağ

Naciye Ümit Bayol

Tufan Süelözgen

Cemal Selçuk İşoğlu

Ferruh Zorlu

Publication Date

June 1, 2015

Submission Date

June 1, 2015

Acceptance Date

-

Published in Issue

Year 1970 Volume: 54 Number: 2

DOI

https://doi.org/10.19161/etd.344113

IZ

https://izlik.org/JA94SS95MK

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RIS / Bibtex
Vancouver
1.Hakan Türk, Mustafa Karabıçak, Sıtkı Ün, Hüseyin Tarhan, Okan Nabi Yalbuzdağ, Naciye Ümit Bayol, Tufan Süelözgen, Cemal Selçuk İşoğlu, Ferruh Zorlu. Radikal sistoprostatektomi yapılan hastalarda prostat kanseri insidansı ve klinik önemi. EJM. 2015 Jun. 1;54(2):65-9. doi:10.19161/etd.344113

Cited By

Evaluation of incidental prostate cancer in patients who underwent radical cystectomy and its effect on survival

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi

https://doi.org/10.30569/adiyamansaglik.1513534

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