The effect of ovulation induction with clomiphene citrate on serum leptin levels in polycystic ovary syndrome

Volume: 55 Number: 1 March 1, 2016
  • Ayşen Güçlü
  • Ümit Nayki
  • Cenk Nayki
  • Mehmet Kulhan
  • Salih Sadık
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The effect of ovulation induction with clomiphene citrate on serum leptin levels in polycystic ovary syndrome

Abstract

Aim: We aimed to assess the effect of ovulation induction with clomiphene citrate on serum leptin levels in infertile women with polycystic ovary syndrome (PCOS). Materials and Methods: Serum leptin levels were evaluated before and after clomiphene citrate (CC) therapy in 40 infertile women with PCOS. According to body mass index (BMI), the patients were divided into two groups as Group 1 (BMI 2) and Group 2 (BMI ≥25 kg/m2) Results: The mean of basal leptin concentrations before CC therapy was 31.7±23.0 ng/mL while it was 35.6±23.0 ng/mL after CC therapy. There was not any significant differrence between basal leptin levels before and after CC therapy (p>0.05). However, before and after CC therapy, serum levels were higher in Group 2 than in Group 1; the difference was statistically significant (p

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Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Ayşen Güçlü

Ümit Nayki

Cenk Nayki

Mehmet Kulhan

Salih Sadık

Publication Date

March 1, 2016

Submission Date

March 1, 2016

Acceptance Date

-

Published in Issue

Year 2016 Volume: 55 Number: 1

DOI

https://doi.org/10.19161/etd.344168

IZ

https://izlik.org/JA38TJ62TS

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RIS / Bibtex
Vancouver
1.Ayşen Güçlü, Ümit Nayki, Cenk Nayki, Mehmet Kulhan, Salih Sadık. Polikistik over sendromunda klomifen sitrat ile ovulasyon indüksiyonunun serum leptin düzeylerine etkisi. EJM. 2016 Mar. 1;55(1):6-10. doi:10.19161/etd.344168

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