THE EFFECT OF PRE- EMPTIVE ANALGESIA IN PATIENTS UNDERGOING LAMINECTOMY

Volume: 41 Number: 3 September 1, 2002
  • Meltem Uyar
  • Abdürrahim Derbent
  • İlkben Günüşen
  • Meral Saklıyan
  • Elvin Kurdoğlu
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THE EFFECT OF PRE- EMPTIVE ANALGESIA IN PATIENTS UNDERGOING LAMINECTOMY

Abstract

The aim of this study was to compare the postoperative analgesic efficacy of pethidine and tramadol administered preemptively in patients undergoing laminectomy. Twenty- five patients undergoing laminectomy ( who didn't take analgesic for 24 hours, ages between 18- 60 years, ASA I- II status, 12 F, 13 M) were included in this study. The protocol was approved by the Instutional Ethical Committee and informed consent were taken from ali patients. Cases were randomised in two groups. In group (1) 1.5 mg.kg1 tramadol, in group (2) 1.5 mg.kg1 pethidine were administered intramuscularly 30 min before surgery. A standardised general anesthesla was maintained with 50 - 50 % O2- /V2O, isoflurane 0.8- 1.5 % after induction with atropine 0.01 mg.kg1, thiopenthal sodium 5 mg.kg1, fentanyl citrate 1.5 mcg. kg1 intravenously, vecuronium was administered 0.1 mg.kg1 for tracheal intubation. The efficacy and duration of analgesia were assessed using visual analogue scale (VAS), where 0= no pain , 10= worst pain imaginable; and a verbal rating scale (VRS) to rate the pain suffered as 4= most severe pain, 0= no pain; at 0.5, 1, 3, 24. hours postoperatively. Tenoxicam (Tilcotif® was administered to the patient when additional analgesic requirement existed. Haemodynamic parameters, additional analgesic drugs, adverse effects were recorded in both study group. Data were analysed using anova, chi- square and student's- t test. There was no significant difference of age, weight, operation time, haemodynamic parameters, and VAS, VRS scores between the two groups. Postoperative 24th hours VAS scores and g-d ^ 24th hours VRS scores were significantly lower when compared baseline values in both groups. İn conclusion, it is suggested that tramadol and pethidine, opioids which have two different mechanism of action, can be used as preemptive analgesics for preventing postoperative pain in laminectomy operations.

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Primary Language

Turkish

Subjects

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Journal Section

-

Authors

Meltem Uyar

Abdürrahim Derbent

İlkben Günüşen

Meral Saklıyan

Elvin Kurdoğlu

Publication Date

September 1, 2002

Submission Date

September 1, 2002

Acceptance Date

-

Published in Issue

Year 2002 Volume: 41 Number: 3

IZ

https://izlik.org/JA88RB54EH

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RIS / Bibtex
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1.Meltem Uyar, Abdürrahim Derbent, İlkben Günüşen, Meral Saklıyan, Elvin Kurdoğlu. LAMİNEKTOMİ UYGULANAN OLGULARDA PRE-EMPTİF ANALJEZİNİN ETKİSİ. EJM [Internet]. 2002 Sep. 1;41(3):151-5. Available from: https://izlik.org/JA88RB54EH

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