Glukoz metabolizma bozukluklarında subklinik aterosklerozun değerlendirilmesi

Elçin Aydın; Cihan Altın; Sinan Emre; Muhteşem Ağıldere; Mustafa Agah Tekindal

doi:10.19161/etd.416642

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Glukoz metabolizma bozukluklarında subklinik aterosklerozun değerlendirilmesi

Öz

Amaç: Diyabet (D) ve prediyabette (PD) vasküler yapıların ve gözün etkilenmesi bilinen bir komplikasyondur. Çalışmamızda PD ve D hastalarında damarsal yapılardaki değişiklikleri karotis intima-media kalınlığı (KIMK) ve epikardiyal yağ kalınlığı (EYK) ölçerek ateroskleroz gelişim riski açısından, gözde ise optik koherens tomografi anjiografi (OKTA) kullanarak retinal ve koroidal vasküler değişiklikler açısından sunmayı amaçladık.

Gereç ve Yöntem: Çalışmamızda Mayıs 2017- Haziran 2017 tarih aralığındaki laboratuar verilerine göre prediyabet ve diyabet tanısı alan hastalarda KIMK, EYK ölçümü ile ateroskleroz riski ve OKTA tekniği ile retinal ve koroidal vasküler değişiklikler; 19 prediyabetik, 12 diyabetik olguda, hastaların yaşı ve cinsiyeti benzer olan 31 normal kan şekeri seviyesine sahip bilinen koroner arter hastalığı olmayan kontrol (K) grubu ile karşılaştırılarak kaydedildi.

Bulgular: Diyabetik 12 hasta (7 kadın, 5 erkek, ortalama yaş 54.2±6.2), PD 19 hasta (ortalama yaş 51±8.6, 11 kadın, 8 erkek) ve 31 K grubu (ortalama yaş 50,9±11.2, 18 kadın, 13 erkek) çalışmaya dahil edilmiştir. KIMK en yüksek diyabetli hastalarda, daha sonra PD ve en az miktarda kontrol hastalarında bulunmuştur. EYK'de gruplar arası farklılık ayırtedilmedi. OKTA verilerine göre en sık bulgu non-perfüzyon, FAZ (foveal avaskuler zon) erozyonu ve venöz göllenme olup en fazla diyabetli hastalarda, sonra PD ve en az K grubunda izlenmiştir.

Sonuç: Subklinik aterosklerozun belirteçleri olan KIMK ve EFT’ye ek olarak retinal vasküler hastalıkların OKTA ile girişimsel olmayan yöntemlerle değerlendirmesinde glukoz metabolizması bozukluğu olan hastaların risk değerlendirilmesinde katkı sağlayacaktır.

Anahtar Kelimeler

Prediyabet,diyabet,ateroskleroz,karotis intima media kalınlığı,epikardiyal yağ kalınlığı,optik koherens tomografi anjiografi.

References

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Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Elçin Aydın ^*
0000-0003-0907-3647
Türkiye

Cihan Altın
0000-0002-3996-5681
Türkiye

Sinan Emre
0000-0001-9829-7268
Türkiye

Muhteşem Ağıldere
0000-0003-4223-7017
Türkiye

Mustafa Agah Tekindal
0000-0002-4060-7048
Türkiye

Publication Date

December 3, 2018

Submission Date

August 13, 2017

Acceptance Date

September 7, 2017

Published in Issue

Year 1970 Volume: 57 Number: 4

DOI

https://doi.org/10.19161/etd.416642

IZ

https://izlik.org/JA69UB62AB

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Vancouver

1.Elçin Aydın, Cihan Altın, Sinan Emre, Muhteşem Ağıldere, Mustafa Agah Tekindal. Glukoz metabolizma bozukluklarında subklinik aterosklerozun değerlendirilmesi. EJM. 2018 Dec. 1;57(4):185-90. doi:10.19161/etd.416642

Assestment of subclinical atherosclerosis in glucose metabolism disorders

Glukoz metabolizma bozukluklarında subklinik aterosklerozun değerlendirilmesi

Öz

Anahtar Kelimeler

Assestment of subclinical atherosclerosis in glucose metabolism disorders

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