Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients
Abstract
Aim: The effect of normal bacterial flora on the immune system is to make it more effective against harmful micro-organisms and to maintain it in readiness for a more rapid response. The purpose of this study was to determine the bacterial flora in the external ear canal and nasal cavities in hemodialysis patients, to compare this with the normal population and to show the microorganisms’ antibiotic susceptibilities.
Materials and Methods: Patients receiving hemodialysis therapy for at least 3 years were included in the study. A control group (n=62) was established consisting of patients with no immune-suppressive condition and presenting to hospital with non-ear symptoms. Swab specimens were taken from all subjects’ external ear canals and nasal cavities. Results of the cultures were recorded and antimicrobial susceptibility test was performed.
Results: The most commonly isolated micro-organisms in the study group were MRCoNS (41%), followed by MSCoNS (15.5%) and diphtheroids (9.8%). The micro-organism most commonly isolated from the nasal cavity in the study group was CoNS (52.7%), of which MRCoNS constituted 69.2%.
Conclusion: We think that infections that play a major role in mortality and morbidity in hemodialysis patients may originate from the external ear canal as much as the nasal cavity, for this reason it is important for micro-organisms colonizing these regions to be eliminated with appropriate treatment on the basis of antibiotic susceptibility tests.
Keywords
References
- 1. Stroman DW, Roland PS, Dohar J, Burt W. Microbiology of normal external auditory canal. Laryngoscope 2001;111(11):2054-9.
- Ucuncu H, Uslu H, Ozbek A, Aktan B, Sutbeyaz Y, Altas E. Comparison of the bacterial flora of the nasal vestibule and cavity in haemodialysis patients. Acta Otorhinolaryngol Ital 2009;29(5):251-4.
- Celik G, Gülcan A, Dikici N, Gülcan E. Prevalence of nasal Staphylococcus aureus carriage in the patients undergoing hemodialysis and evaluation of risk factors and laboratory parameters. Ren Fail 2011;33(5):494-8.
- Brook I. Microbiological studies of the bacterial flora of the external auditory canal in children. Acta Otolaryngol 1981;91(3-4):285-7.
- Wright DN, Alexander JM. Effect of water on the bacterial flora of swimmer’s ears. Arch Otolaryngol 1974;99(1):15-8.
- Salit IE, Miller B, Wigmore M, Smith JA. Bacterial flora of the external canal in diabetics and non-diabetics. Laryngoscope 1982;92(6Pt1):672-3.
- European Committee on Antimicrobial Susceptibility Testing. Clinical Breakpoints tables of interpretation of MIC’s and zone diameters. Version 6.0, (Dec.31,2016). Available from: http//www.eucast.org
- Ostfeld E, Rubinstein E, Gazit E, Smetana Z. Effect of systemic antibiotics on the microbial flora of the external ear canal in hospitalized children. Pediatrics 1977;60(3):364-6.
Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Authors
Korhan Kılıç
*
0000-0001-6048-034X
Türkiye
Eylül Derman
0000-0002-4533-0308
Türkiye
Muhammed Sedat Sakat
0000-0001-9588-1725
Türkiye
Mustafa Sıtkı Gözeler
0000-0002-9716-9579
Türkiye
Hakan Uslu
0000-0003-1478-7441
Türkiye
Furkan Şengöz
0000-0001-9109-2681
Türkiye
Publication Date
June 28, 2019
Submission Date
January 5, 2018
Acceptance Date
May 9, 2018
Published in Issue
Year 1970 Volume: 58 Number: 2