Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data
Abstract
Aim: We aimed to investigate the alteration and distribution of seroprevalence of hepatitis B and hepatitis C within
the years according to age groups in patients who applied to our hospital.
Materials and Methods: The patients have been evaluated for six years retrospectively who were admitted to third
step hospital in Istanbul. The duplicate results of patients who submitted more than one application within the same
year were excluded from this study. Male and female patients were divided into four age groups as 0-14, 14-25, 25-
49 and over 49 years old. Electrochemiluminescence method (Roche Cobas 6000, Germany) was used for HBsAg
and anti-HCV assays.
Results: HBsAg positivity was 2.97% and anti-HCV positivity was 1.35%. HBsAg positivity was higher in males, and
anti-HCV positivity was higher in females. No significant increase in seroprevalences of anti-HCV and HBsAg was
observed during the six years observation period. HBsAg seroprevalences decreased in years especially in 0-14 and
14-25 year-old male groups. HBsAg seroprevalence was not decreased in the other age groups over the years.
There was no significant difference in anti-HCV seroprevalence over the years. HBsAg positivity was higher in males
and anti-HCV positivity was higher in females. Anti-HCV and HBsAg seroprevalence were not significantly differed
over the years.
Conclusion: It was remarkable that HBsAg positivity rate had decreased over the years especially in 0-14 and 14-25
year-old males. Seroprevalence of HBsAg did not decrease in years in other age groups. There was no significant
difference in the seroprevalence of anti-HCV during the measurement period.
Keywords
References
- You CR, Lee SW, Jang JW, Yoon S K. Update on hepatitis B virus infection. World J Gastroenterol 2014;20(37):13293-305.
- Zampino R, Boemio A, Sagnelli C, et al. Hepatitis B virus burden in developing countries. World J Gastroenterol 2015;21(42):11941-53.
- Caccamo G, Saffioti F, Raimondo G. Hepatitis B virus and hepatitis C virus dual infection. World J Gastroenterol 2014;28:20(40):14559-67.
- WHO Hepatitis B. Available from: http://www.who.int/news-room/fact-sheets/detail/hepatitis-b.
- Ergunay K, Balaban Y, Cosgun E, Hascelik G. Epidemiological trends in HBV infections at a reference centre in Turkey: An 11-year retrospective analysis. Ann Hepatol 2012;11(5):672-8.
- WHO Hepatitis C. Available from: http://www.who.int/news-room/fact-sheets/detail/hepatitis-c.
- Akarca US. Chronic hepatitis B. A guideline to diagnosis, approach, management, and follow‐up 2007. Turkish Association for the Study of Liver. Turk J Gastroenterol 2008;19(4):207‐30.
- Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B virus infection: Epidemiology and vaccination. Epidemiol Rev 2006;28(1):112-25.
Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Authors
Tuba Kuruoğlu
0000-0003-3805-367X
Türkiye
Defne Gümüş
0000-0003-4070-6924
Türkiye
Fatma Kalaycı
0000-0002-0028-5646
Türkiye
Kıvanç Şerefhanoğlu
0000-0003-0585-8797
Türkiye
Publication Date
June 28, 2019
Submission Date
March 2, 2018
Acceptance Date
May 25, 2018
Published in Issue
Year 1970 Volume: 58 Number: 2