Can neutrophil / lymphocyte ratio be used as a predictor of the hepatic fibrosis in chronic hepatitis B patients
Abstract
Aim: Assessing fibrosis in chronic hepatitis B (CHB) patients is important in preventing cirrhosis and hepatocellular
cancer development. Liver biopsy is the golden standard in evaluating fibrosis. Because liver biopsy is invasive and
has complications, non-invasive tests to demonstrate liver histopathology have become more important. There are
some studies that demonstrate the relationship between neutrophil/lymphocyte ratio (NLR) and fibrosis in nonalcoholic steatohepatitis and CHB patients. The purpose of the present study was to evaluate the relationship
between NLR and hepatic fibrosis in CHB patients.
Materials and Methods: Sixty-seven patients who were under follow-up by our hepatology outpatient clinic and had
liver biopsies were reviewed retrospectively. Demographics, laboratory parameters and values measured with liver
biopsy were recorded for each patient.
Results: The mean age of the study population was 48.6±11.7 years. Seventeen women (25.4%) and 50 men
(69.6%) were included in the study. Fibrosis degree was 0 in 8 patients, 1 in 15, 2 in 8, 3 in 18, 4 in 7, 5 in 9, and 6 in
2. No significant relationship was found between fibrosis degree which was detected by liver biopsy and NLR in CHB
patients (p=0.54).
Conclusion: NLR ratio was not considered to be an effective parameter to demonstrate fibrosis in CHB patients.
Keywords
References
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Details
Primary Language
Turkish
Subjects
Health Care Administration
Journal Section
Research Article
Authors
Sevil Özer Sarı
*
0000-0001-8830-0371
Türkiye
Hüseyin Köseoğlu
0000-0002-2197-7473
Türkiye
Mustafa Akar
Türkiye
Tevfik Solakoğlu
0000-0002-5735-4200
Türkiye
Osman Ersoy
0000-0002-1364-5962
Türkiye
Publication Date
June 28, 2019
Submission Date
February 15, 2018
Acceptance Date
May 23, 2018
Published in Issue
Year 1970 Volume: 58 Number: 2