TNF-Alfa Inhibitörleri Ile Tedavi Seyrinde Gelişen Alerjik Reaksiyonlar

Sevim Bavbek

doi:10.19161/etd.648098

EN TR

Hypersensitivity reactions to TNF-α inhibitors

Abstract

Patients with chronic inflammatory and autoimmune diseases are repeatedly exposed to TNF-α inhibitors. Currently five TNF-α inhibitors such as infliximab, etanercept, adalimumab, golimumab and certolizumab are available. Although these agents are generally well tolerated and safe, systemic such as urticaria, angioedema and anaphylaxis or local hypersensitivity reactions as local injection site reaction have been reported with the use of these drugs. Intravenous or subcutaneous rapid drug desensitization is a valid therapeutic option to preclude their use in sensitized patients.

Keywords

TNF-α inhibitors,injection site reaction,systemic hypersensitivity reaction,biological agents,desensitization.

References

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Details

Primary Language

Turkish

Subjects

-

Journal Section

Other

Authors

Sevim Bavbek ^*
0000-0002-7884-0830
Türkiye

Publication Date

October 25, 2019

Submission Date

October 19, 2018

Acceptance Date

August 15, 2019

Published in Issue

Year 1970

DOI

https://doi.org/10.19161/etd.648098

IZ

https://izlik.org/JA97JH68AX

Cite

RIS / Bibtex

Vancouver

1.Sevim Bavbek. TNF-Alfa Inhibitörleri Ile Tedavi Seyrinde Gelişen Alerjik Reaksiyonlar. EJM. 2019 Oct. 1;1-5. doi:10.19161/etd.648098

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Hypersensitivity reactions to TNF-α inhibitors

Hypersensitivity reactions to TNF-α inhibitors

Abstract

Keywords