TNF-Alfa Inhibitörleri Ile Tedavi Seyrinde Gelişen Alerjik Reaksiyonlar

Sevim Bavbek

doi:10.19161/etd.648098

EN TR

Hypersensitivity reactions to TNF-α inhibitors

Abstract

Patients with chronic inflammatory and autoimmune diseases are repeatedly exposed to TNF-α inhibitors. Currently five TNF-α inhibitors such as infliximab, etanercept, adalimumab, golimumab and certolizumab are available. Although these agents are generally well tolerated and safe, systemic such as urticaria, angioedema and anaphylaxis or local hypersensitivity reactions as local injection site reaction have been reported with the use of these drugs. Intravenous or subcutaneous rapid drug desensitization is a valid therapeutic option to preclude their use in sensitized patients.

Keywords

TNF-α inhibitors,injection site reaction,systemic hypersensitivity reaction,biological agents,desensitization.

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

Diğer

Yazarlar

Sevim Bavbek ^*
0000-0002-7884-0830
Türkiye

Yayımlanma Tarihi

25 Ekim 2019

Gönderilme Tarihi

19 Ekim 2018

Kabul Tarihi

15 Ağustos 2019

Yayımlandığı Sayı

Yıl 1970

DOI

https://doi.org/10.19161/etd.648098

IZ

https://izlik.org/JA97JH68AX

Kaynak Göster

RIS / Bibtex

Vancouver

1.Sevim Bavbek. TNF-Alfa Inhibitörleri Ile Tedavi Seyrinde Gelişen Alerjik Reaksiyonlar. ETD. 01 Ekim 2019;1-5. doi:10.19161/etd.648098

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https://doi.org/10.1089/ped.2025.0003

TNF-Alfa Inhibitörleri Ile Tedavi Seyrinde Gelişen Alerjik Reaksiyonlar

Hypersensitivity reactions to TNF-α inhibitors

Abstract

Keywords