EN
TR
F18 FDG PET/CT findings in cat-scratch disease: a case report
Abstract
Cat-scratch disease is a bacterial infection caused by Bartonella Henselae which affects lymph nodes that drain the sites of inoculation. Axillary, cervical and inguinal lymph nodes are the most common regions being involved. The disease can be considered as an FDG-avid disease, given the granulomatous nature of the infection. We herein report F18 FDG PET/CT findings of a 49-year-old woman, who has abdominal lymphadenopathy revealed on ultrasonography (USG). PET/CT scan demonstrated bilateral axillary and abdominopelvic hypermetabolic enlarged lymph nodes with SUVmax value of 6.2 to 18.5. Moreover, a hypermetabolic hypodense lesion in the spleen with SUVmax value of 11.3 was detected. Excisional biopsy of the axillary lymph node performed. Based on clinical-histopathological findings and the history of being scratched by a cat recently, the patient was diagnosed with cat-scratch disease. In conclusion, cat-scratch disease represents a cause of false-positive results in oncological PET/CT scans. Furthermore, PET/CT may have a role in revealing the applicable biopsy area and showing the additional involvement sites. Keywords: Cat-Scratch Disease, PET-CT, Lymphadenopathy.
Keywords
References
- Bergman AM, Groothedde JW, Schellekens JFP, van Embden JD, Ossewaarde JM, Schouls LM. Etiology of catscratch disease: a comparison of polymerase chain reaction detection of Bartonella and Afipia felis DNA with serology and skin tests. J Infect Dis. 1995; 171 (4): 916-23.
- Mosbacher ME, Klotz S, Klotz J, Pinnas JL. Bartonella henselae and the potential for arthropod vector-borne transmission. Vector Borne Zoonotic Dis. May 2011; 11 (5): 471-7.
- Markaki S, Sotiropoulou M, Papaspirou P, Lazaris D. Cat-scratch disease presenting as a solitary tumour in the breast: report of three cases. Eur J Obstet Gynecol Reprod Biol. 2003; 106 (2): 175-8.
- Spach DH, Kaplan SL. Microbiology, epidemiology, clinical manifestations, and diagnosis of cat scratch disease. In: UpToDate, Post TW (Ed), UpToDate, Waltham, MA. (Accessed on May 28, 2020).
- Vaidyanathan S, Patel CN, Scarsbrook AF, Chowdhury FU. FDG PET/CT in infection and inflammation--current and emerging clinical applications. Clin Radiol. 2015; 70 (7): 787-800.
- Asano S. Granulomatous lymphadenitis. J Clin Exp Hematop 2012; 52 (1): 1–16.
- Sander A, Berner R, Ruess M. Serodiagnosis of cat scratch disease; response to Bartonella henselae in children and review of diagnostic methods. Eur J Clin Microbiol Infect Dis. 2001; 20 (6): 392-401.
- Lin E, Alavi A. PET and PET/CT A clinical guide, Second edition. Thieme Medical Publishers, Inc.2009. P:25.
Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Case Report
Publication Date
September 13, 2021
Submission Date
May 29, 2020
Acceptance Date
September 8, 2020
Published in Issue
Year 1970 Volume: 60 Number: 3