Araştırma Makalesi

Comparing the efficacy of imaging techniques in detecting myometrial invasion, cervical involvement and pelvic lymph-nodal metastasis in endometrial cancer

Cilt: 61 Sayı: 4 12 Aralık 2022
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Comparing the efficacy of imaging techniques in detecting myometrial invasion, cervical involvement and pelvic lymph-nodal metastasis in endometrial cancer

Abstract

Aim: To compare sensitivity, specificity, positive predictive and negative predictive value of preoperative imaging techniques for detecting myometrial invasion, cervix involvement, and alsopelvic lymph nodal metastasis in endometrial cancer Materials and Methods: The medical records of patients who underwent an operation for endometrial cancer in the years between 2005 and 2017 were collected from the database at our institution. Preoperative imaging reports of 252 ultrasonography (USG), 89 computerized tomographies (CT),147 magnetic resonance imaging (MRI) of patients with endometrial cancer, and postoperative pathologic reports were collected and compared. Results: In our study 252 ultrasonography (USG), 89 computerized tomography (CT), 147 magnetic resonance imaging (MRI) examinations were evaluated. Among deep myometrial invasion; all imaging modalities have low specificities (respectively 26.7%, 37.9%, and 32.4%) but higher sensitivities (respectively 68.5%, 79.1%, and 89.4%). To rule out cervical invasion all modalities have high and comparable sensitivities (respectively 98.3%, 95.0%, and 87.0%). On the other hand, USG has superiority to detect cervical invasion over CT and MRI (respectively 71.4%, 15.4%, and 22.7%). CT has much highersensitivity than MRI for detection of pelvic lymph node metastasis (87.5% vs 53.1%). Conclusion: Preoperative imaging modalities have high sensitivities for deep myometrial invasion, but low detection rates for cervical involvement and pelvic lymph node metastasis. MRI should be the preferred modality for myometrial invasion, on the other hand, The USG is much better to detect cervical involvement. CT has superiority on other imaging modalities among lymph node metastasis.

Keywords

Destekleyen Kurum

retrospektif çalışma verileri uludağ üniversitesinden temin edilmiştir

Kaynakça

  1. Kinkel K et al. Radiologic staging in patients with endometrial cancer: a meta-analysis. Radiology. 1999 Sep; 212 (3): 711-8.
  2. Boronow RC, Morrow CP, Creasman WT, et al. Surgical staging in endometrial cancer: clinical- pathologic findings of a prospective study. Obstet Gynecol 1984; 63:825-832.
  3. Morrow CP, Curtin JP, Townsend DG, Tumors of the endometrium. In: Morrow CP, Curtin JP,eds.Synopsis of gynecologic oncology.5 th ed. New York, NY: Churchill Livingstone, 1998:151-185.
  4. Larson DM, Connor GP, Broste SK, Krawisz BR. Johnson KK. Prognostic significance of gross myometrial invasion with endometrial cancer. Obstet Gynecol 1996;88: 394- 398.
  5. Kodama S. Kase H. Tanaka K. Matsui K. Multivariate analysis of prognostic factors in patients with endometrial cancer. Int. J Gynaecol Obstet 1996: 53:23-30
  6. Pecorelli S. Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obstet. 2009; 105(2): 103–104, indexed in Pubmed: 19367689.
  7. Alcázar JL1, Gastón B2, Navarro B3, Salas R4, Aranda J5, Guerriero S6. Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with endometrial cancer: a systematic review and meta-analysis.J Gynecol Oncol. 2017 Nov;28(6): e86.
  8. Savelli L1, Ceccarini M, Ludovisi M, Fruscella E, De Iaco PA, Salizzoni E, Mabrouk M, Manfredi R, Testa AC, Ferrandina G.Preoperative local staging of endometrial cancer: transvaginal sonography vs. magnetic resonance imaging.Ultrasound Obstet Gynecol. 2008 May;31(5):560-6.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Yayımlanma Tarihi

12 Aralık 2022

Gönderilme Tarihi

23 Mayıs 2022

Kabul Tarihi

10 Temmuz 2022

Yayımlandığı Sayı

Yıl 2022 Cilt: 61 Sayı: 4

DOI

https://doi.org/10.19161/etd.1209113

IZ

https://izlik.org/JA34ZL87GN

Kaynak Göster

RIS / Bibtex
Vancouver
1.Alpay Yılmaz, Fatih Yılmaz, H. Öztürk Şahin, Fatma Öz Atalay, Dilek Uysal, Hakan Ozan. Comparing the efficacy of imaging techniques in detecting myometrial invasion, cervical involvement and pelvic lymph-nodal metastasis in endometrial cancer. ETD. 01 Aralık 2022;61(4):647-50. doi:10.19161/etd.1209113

Cited By

Optimizing Final Pathology Determination in Endometrial Cancer: The Role of PET/CT, MRI, and Biopsy in Serous, Mixed Cell, Clear Cell, and Grade 3 Endometrioid Subtypes

Diagnostics

https://doi.org/10.3390/diagnostics15060731

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