Araştırma Makalesi

Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center

Cilt: 65 Sayı: 2 10 Haziran 2026
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Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center

Öz

Aim: The aim of this study is to analyze the demographic characteristics of patients with a cytology result of Atypical Squamous Cells - Cannot Exclude High-Grade Squamous Intraepithelial Lesion evaluated at the Colposcopy Unit of a tertiary referral center between 2010 and 2016, and to determine the extent of their concordance with the established risk factors for cervical cancer development in the literature. Materials and Methods: Medical records of patients evaluated at the colposcopy unit with ASC-H cytology results between January 2010 and July 2016 were retrospectively reviewed. Demographic and obstetric data were retrieved, and descriptive statistical analyses were conducted. Results: The mean age of the 62 patients with ASC-H was 41 years, and the mean age at first sexual intercourse was 21.2 years. Sociodemographic analysis revealed a predominantly low socioeconomic profile; specifically, illiterate or primary school graduates accounted for 87% of the cohort, 88% were housewives, and 62% were internal migrants. In addition, 61% of the patients reported no use of contraception. Collectively, indicators such as early age at first intercourse, multiparity, and low socioeconomic status (characterized by internal migration and limited educational/workforce participation) constitute a distinct risk profile for ASC-H. Conclusions: The high frequency of ASC-H observed particularly among patients with low socioeconomic status underscores the necessity of making national cervical cancer screening programs more accessible to these underserved populations, potentially through mobile screening units or targeted educational campaigns. Furthermore, these findings suggest that clinicians should adopt a more holistic approach by considering not only the cytological result but also the patient's social risk profile to formulate effective, personalized management plans.

Anahtar Kelimeler

Destekleyen Kurum

Yoktur

Etik Beyan

Bu çalışma, Helsinki Bildirgesi prensiplerine uygun olarak yürütülmüştür. Çalışma için etik kurul onayı İstanbul Eğitim ve Araştırma Hastanesi Klinik Araştırmalar Etik Kurulu'ndan alınmıştır (Tarih: 11.11.2016; Karar No: 859).

Teşekkür

Yoktur.

Kaynakça

  1. Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2024;74(3):229-63.
  2. Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin 2021;71(3):209-49.
  3. Alam Z, Shafiee Hanjani L, Dean J, Janda M. Cervical Cancer Screening Among Immigrant Women Residing in Australia: A Systematic Review. Asia Pac J Public Health 2021;33(8):816-27.
  4. Ferlay J, Forman D, Mathers CD, Bray F. Breast and cervical cancer in 187 countries between 1980 and 2010. Lancet 2012;379(9824):1390-1.
  5. Lin L, Li Z, Yan L, Liu Y, Yang H, Li H. Global, regional, and national cancer incidence and death for 29 cancer groups in 2019 and trends analysis of the global cancer burden, 1990-2019. J Hematol Oncol 2021;14(1):197.
  6. Solomon D, Davey D, Kurman R, et al. The 2001 Bethesda System: terminology for reporting results of cervical cytology. Jama 2002;287(16):2114-9.
  7. Nayar R, Wilbur DC. The Bethesda System for Reporting Cervical Cytology: A Historical Perspective. Acta Cytol 2017;61(4-5):359-72.
  8. Tokalıoğlu AA, Alcı A, Oktar O, et al. Do HPV 16 positive/ASC-H cervical cancer screening results predict CIN 2+ better than other high-risk HPV subtypes? J Turk Ger Gynecol Assoc 2024;25(2):90-5.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Cerrahi (Diğer)

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

10 Haziran 2026

Gönderilme Tarihi

30 Aralık 2025

Kabul Tarihi

27 Şubat 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 65 Sayı: 2

Kaynak Göster

APA
Kandemir, S., & Verit, F. F. (2026). Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center. Ege Tıp Dergisi, 65(2), 305-312. https://doi.org/10.19161/etd.1852360
AMA
1.Kandemir S, Verit FF. Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center. ETD. 2026;65(2):305-312. doi:10.19161/etd.1852360
Chicago
Kandemir, Selim, ve Fatma Ferda Verit. 2026. “Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center”. Ege Tıp Dergisi 65 (2): 305-12. https://doi.org/10.19161/etd.1852360.
EndNote
Kandemir S, Verit FF (01 Haziran 2026) Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center. Ege Tıp Dergisi 65 2 305–312.
IEEE
[1]S. Kandemir ve F. F. Verit, “Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center”, ETD, c. 65, sy 2, ss. 305–312, Haz. 2026, doi: 10.19161/etd.1852360.
ISNAD
Kandemir, Selim - Verit, Fatma Ferda. “Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center”. Ege Tıp Dergisi 65/2 (01 Haziran 2026): 305-312. https://doi.org/10.19161/etd.1852360.
JAMA
1.Kandemir S, Verit FF. Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center. ETD. 2026;65:305–312.
MLA
Kandemir, Selim, ve Fatma Ferda Verit. “Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center”. Ege Tıp Dergisi, c. 65, sy 2, Haziran 2026, ss. 305-12, doi:10.19161/etd.1852360.
Vancouver
1.Selim Kandemir, Fatma Ferda Verit. Retrospective cross-sectional analysis of the sociodemographic characteristics of cases with atypical squamous cells - cannot exclude high-grade squamous intraepithelial lesion detected at the colposcopy unit of a tertiary referral center. ETD. 01 Haziran 2026;65(2):305-12. doi:10.19161/etd.1852360

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