KRONİK İDİOPATİK ÜRTİKERDE OTOLOG SERUM TESTİ

Cilt: 42 Sayı: 1 1 Mart 2003
  • Nihal Mete
  • Okan Gülbahar
  • Aytül Sin
  • Ali Kokuludağ
  • Filiz Sebik
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AUTOLOGOUS SERUM TEST POSITIVITY IN PATIENTS WITH CHRONIC IDIOPATHIC URTICARIA

Abstract

The etiology of chronic urticaria cannot be identified in more than 75% of the patients even after an exhaustive search. However, recent studies indicate that autoimmune mechanisms may be involved in the etiology in patients with chronic idiopathic urticaria (CIU). In this study, 60 patients who presented to the allergy clinic with urticaria were studied to determine the positivity of the autologous serum test in CIU. Twenty-eight patients were diagnosed with CIU. Patients were injected with 50µl autologous serum in the forearm intradermally. Histamine and normal saline were also injected as a positive and negative control, respectively. An area of skin redness that is at least 1.5 mm larger in diameter than that observed with saline was considered positive. The autologous serum test was positive in 82.1% of the patients with CIU. The urticaria symptoms were more severe and unresponsive to antihistaminic therapy in patients with a positive autologous serum test. Therefore, immunomodulatory therapies may be indicated in the CIU patients with a positive autologus serum test. In conclusion, the autologous serum test appears to be useful tool in CIU especially in identification of the patients who are unlikely to respond to the conventional antihistaminic therapy.

Keywords

Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

-

Yazarlar

Nihal Mete

Okan Gülbahar

Aytül Sin

Ali Kokuludağ

Filiz Sebik

Yayımlanma Tarihi

1 Mart 2003

Gönderilme Tarihi

1 Mart 2003

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2003 Cilt: 42 Sayı: 1

IZ

https://izlik.org/JA89EH46HU

Kaynak Göster

RIS / Bibtex
Vancouver
1.Nihal Mete, Okan Gülbahar, Aytül Sin, Ali Kokuludağ, Filiz Sebik. KRONİK İDİOPATİK ÜRTİKERDE OTOLOG SERUM TESTİ. ETD [Internet]. 01 Mart 2003;42(1):25-9. Erişim adresi: https://izlik.org/JA89EH46HU

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