KRONİK MELATONİN UYGULAMASININ SIÇAN OVARYUMUNA ETKİLERİNİN HİSTOLOJİK OLARAK İNCELENMESİ

Cilt: 43 Sayı: 1 1 Mart 2004
  • Kemal Ergin
  • H. Kübra Başaloğlu
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HISTOLOGIC EVALUATION OF THE EFFECTS OF CHRONIC MELATONIN ADMINISTRATION ON RAT OVARIAN TISSUE

Abstract

There are many studies about the effects of melatonin on reproductive system. This study was performed on 26 female Wistar rats divided into two groups; the control group and the experimental group. The experimental group was injected with 1 mg/kg/day melatonin subcutaneusly for 21 days. Ovaries of both groups were investigated under light microscope. Compared to the control group, findings indicating atresia of most of the follicles, vasodilatation of vessels in stroma, medulla and follicle's theca layer were observed in the experimental group. In addition, Graaf follicle numbers were significantly low in the experimental group. As a result, chronic melatonin administration caused morphologic changes on ovaries accelerating atresia of follicles which might lead to negative effects on fertility.

Keywords

Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

-

Yazarlar

Kemal Ergin

H. Kübra Başaloğlu

Yayımlanma Tarihi

1 Mart 2004

Gönderilme Tarihi

1 Mart 2004

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2004 Cilt: 43 Sayı: 1

Kaynak Göster

Vancouver
1.Kemal Ergin, H. Kübra Başaloğlu. KRONİK MELATONİN UYGULAMASININ SIÇAN OVARYUMUNA ETKİLERİNİN HİSTOLOJİK OLARAK İNCELENMESİ. ETD [Internet]. 01 Mart 2004;43(1):41-5. Erişim adresi: https://izlik.org/JA34RB68SN

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