HISTOLOGIC EVALUATION OF THE EFFECTS OF CHRONIC MELATONIN ADMINISTRATION ON RAT OVARIAN TISSUE

Volume: 43 Number: 1 March 1, 2004
  • Kemal Ergin
  • H. Kübra Başaloğlu
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HISTOLOGIC EVALUATION OF THE EFFECTS OF CHRONIC MELATONIN ADMINISTRATION ON RAT OVARIAN TISSUE

Abstract

There are many studies about the effects of melatonin on reproductive system. This study was performed on 26 female Wistar rats divided into two groups; the control group and the experimental group. The experimental group was injected with 1 mg/kg/day melatonin subcutaneusly for 21 days. Ovaries of both groups were investigated under light microscope. Compared to the control group, findings indicating atresia of most of the follicles, vasodilatation of vessels in stroma, medulla and follicle's theca layer were observed in the experimental group. In addition, Graaf follicle numbers were significantly low in the experimental group. As a result, chronic melatonin administration caused morphologic changes on ovaries accelerating atresia of follicles which might lead to negative effects on fertility.

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Primary Language

Turkish

Subjects

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Journal Section

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Authors

Kemal Ergin

H. Kübra Başaloğlu

Publication Date

March 1, 2004

Submission Date

March 1, 2004

Acceptance Date

-

Published in Issue

Year 2004 Volume: 43 Number: 1

IZ

https://izlik.org/JA34RB68SN

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1.Kemal Ergin, H. Kübra Başaloğlu. KRONİK MELATONİN UYGULAMASININ SIÇAN OVARYUMUNA ETKİLERİNİN HİSTOLOJİK OLARAK İNCELENMESİ. EJM [Internet]. 2004 Mar. 1;43(1):41-5. Available from: https://izlik.org/JA34RB68SN

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