RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ

Çiğdem ELBEK Çubukçu

EN TR

EFFECTS OF SYSTEMIC FLUORIDE INTAKE ON RAT GASTRIC MUCOSA

Abstract

This paper presents a study that was carried out to determine the adverse effects of graded doses of fluoride on rat gastric mucosa. Fifty Swiss Albino rats were used. Experimental groups received a solution of 0.5, 5, 50, and 500 ppm fluoride. Control group had distilled water. These solutions administered to the experimental animals during 30 days. In Group V experiment duration was 12 h. In all experimental groups, the rat stomachs were prepared for stereomicroscopic and light microscopic investigation to identify the morphologic and histologic changes. H&E and PAS stains were used for cellular detail. The most specific finding in high fluoride concentrations was mucus layer loss. The fluoride injury was limited in the luminal one-third of the mucosa. Fluoride damaged histological structure in gastric mucosa without causing any injury macroscopically.

Keywords

Systemic Fluoride Intake, Rat Gastric Mucosa

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Çiğdem ELBEK Çubukçu

Publication Date

June 1, 2005

Submission Date

June 1, 2005

Acceptance Date

-

Published in Issue

Year 2005 Volume: 44 Number: 2

IZ

https://izlik.org/JA58ZJ26BY

Cite

RIS / Bibtex

APA

Çubukçu, Ç. E. (2005). RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ. Ege Tıp Dergisi, 44(2), 81-85. https://izlik.org/JA58ZJ26BY

AMA

1.Çubukçu ÇE. RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ. EJM. 2005;44(2):81-85. https://izlik.org/JA58ZJ26BY

Chicago

Çubukçu, Çiğdem ELBEK. 2005. “RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ”. Ege Tıp Dergisi 44 (2): 81-85. https://izlik.org/JA58ZJ26BY.

EndNote

Çubukçu ÇE (June 1, 2005) RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ. Ege Tıp Dergisi 44 2 81–85.

IEEE

[1]Ç. E. Çubukçu, “RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ”, EJM, vol. 44, no. 2, pp. 81–85, June 2005, [Online]. Available: https://izlik.org/JA58ZJ26BY

ISNAD

Çubukçu, Çiğdem ELBEK. “RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ”. Ege Tıp Dergisi 44/2 (June 1, 2005): 81-85. https://izlik.org/JA58ZJ26BY.

JAMA

1.Çubukçu ÇE. RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ. EJM. 2005;44:81–85.

MLA

Çubukçu, Çiğdem ELBEK. “RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ”. Ege Tıp Dergisi, vol. 44, no. 2, June 2005, pp. 81-85, https://izlik.org/JA58ZJ26BY.

Vancouver

1.Çiğdem ELBEK Çubukçu. RAT GASTRİK MUKOZASINDA SİSTEMİK FLORİD ALIMININ ETKİLERİ. EJM [Internet]. 2005 Jun. 1;44(2):81-5. Available from: https://izlik.org/JA58ZJ26BY