Ascites formation in the course of refractory myeloma and response to intra-peritoneal dexametasone treatment
Abstract
Multiple myeloma (MM) is a plasma cell dyscrasia characterized by the malignant proliferation of a plasma cell clone. Ascites is a rare complication of MM and generally occurs because of portal hypertension due to the infiltration of liver by plasma cells. Infrequently, ascites is detected as a result of peritoneal infiltration by plasma cells. Ascites in the course of myeloma has a progressive course and is refractory to high dose chemotherapy. A refractory myeloma case with massive ascites due to peritoneal infiltration and responding to intra-peritoneal dexametasone treatment is presented.
Abstract
Multipl Myelom (MM) plazma hücre klonunun malign proliferasyonu ile karakterize bir plazma hücre diskrazisidir. Asit oluşumu MM'un nadir bir komplikasyonudur ve genellikle karaciğerin plazma hücreleri ile infiltrasyonu sonucu meydana gelen portal hipertansiyona bağlıdır. Asit nadiren peritonun plazma hücre infiltrasyonu sonucu da görülebilir. Myelom seyrinde asit oluşumu progresif seyreder ve yüksek doz kemoterapiye refrakterdir. Peritoneal infiltrasyona bağlı masif asit ile başvuran ve intraperitoneal deksametazon tedavisine yanıt veren bir refrakter myelom olgusu sunulmaktadır.
Details
| Other ID | JA23ZH98GF |
|---|---|
| Journal Section | Case Reports |
| Authors | |
| Publication Date | March 1, 2016 |
| Submission Date | March 1, 2016 |
| Published in Issue | Year 2016Volume: 55 Issue: 1 |
